The exam evaluates foundational biological concepts, including cell structures, diffusion, photosynthesis, enzyme activity, genetics, immunity, and the human circulatory system. Key topics include adaptations in plants and animals, the impact of pathogens, enzyme function at various temperatures, and cholesterol's role in cardiovascular health. Additional areas of focus involve aseptic techniques in microbiology, the effect of BMI on health, and the implications of exercise on physiological responses. Keywords: GCSE Biology, Foundation Tier, cell structures, photosynthesis, enzyme activity, immunity, genetics, cardiovascular health, BMI, microbiology.