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Biology WBI15/01 October 2023 | Edexcel International A Level Past Papers With Mark Scheme

1. gene technology—recombinant DNA formation, restriction endonuclease, plasmid roles, transcription factor inhibition of gene expression
2. neurobiology—pupil reflex mechanism, photoreceptors (opsin + retinal), neurotransmitter effects (MDMA/nicotine), pupil diameter/area calculations
3. MRI brain imaging—lesion volume measurement, contrast dye function, ADEM impact on motor coordination via myelin loss
4. cardiovascular system—heart rate vs lifespan correlation, ECG interpretation, sympathetic nervous response on cardiac output, human lifespan variation factors
5. synaptic transmission—neurotransmitter release and receptor binding, serotonin biosynthesis using genetically modified E. coli, time-dependent concentration changes in bioproduction
6. hormonal control—adrenaline effect on heart/breathing rate, Daphnia heart rate modulation by nicotine and adrenaline, phytochrome/gibberellin interaction in photoperiodic flowering
7. muscle physiology—sliding filament theory of contraction, energy usage in muscle function, ostrich muscle mass comparisons, hypothalamic thermoregulation mechanisms in endotherms

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