The OCR GCSE Biology Paper 1 (June 2022) covers core topics like DNA structure, protein synthesis, respiration, and the endocrine system. It emphasizes human physiology, homeostasis, and the impact of environmental changes on biodiversity. Practical investigations explore bacterial growth, transpiration rates, and protein tests. Key themes include genetic inheritance, ecological balance, and adaptations in animals like elephants and puffins. The paper also addresses the role of hormones in plant growth, the maintenance of body temperature, and ethical considerations in conservation and disease management. Experimental design and data analysis are central to the assessment.