The OCR GCSE Biology Paper 2 (June 2022) emphasizes ecological relationships, genetic inheritance, and disease management. Topics include the circulatory system, food webs, antibiotic resistance, and malaria control. Practical investigations explore transpiration, aseptic techniques, and bacterial culture analysis. The paper highlights the impact of human activity on biodiversity, natural selection processes, and ethical considerations in genetic engineering. Data interpretation, experimental design, and the application of biological concepts in conservation and public health are integral components of the assessment.