This OCR GCSE Chemistry (Gateway Science) Paper 3 (Higher Tier) emphasizes fundamental and advanced concepts, including periodic trends, bonding, isotopes, and stoichiometry. Topics feature chromatography, nanoparticle applications, biofuels, and electrolysis. The paper also tests practical applications like distillation, reaction rate analysis, and titration. Data interpretation is required for graphing, bond energy calculations, and reaction profiles. Environmental chemistry, metal extraction, and acid-base reactions are integrated, alongside ionic equations and energy changes in chemical processes.