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Biology (A) 9BN0/02 May June 2019

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1. Cell Membranes and Transport: Structure of the phospholipid bilayer, functions of membrane proteins, facilitated diffusion, active transport, and the role of CFTR in cystic fibrosis. 2. Genetics and Disease: Hardy-Weinberg calculations for allele frequency, effects of CFTR mutations on disease severity, and genetic probability in population studies. 3. Exercise Physiology and Homeostasis: Role of the brain in heart rate and sweating regulation after exercise, negative feedback mechanisms, and risks of excessive physical activity. 4. Muscle Contraction and Biochemistry: Actin and myosin interactions, ATPase function in muscle fibers, and the importance of primary protein structure in enzymatic function. 5. Photosynthesis and Respiration: ATP synthesis in glycolysis, Krebs cycle, and electron transport chain, energy storage, and transfer in metabolic pathways. 6. Cancer and Genetic Risk Factors: Prostate cancer development, effects of diet and sugar intake, genetic predisposition in twins, and statistical analysis of cancer causes.
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