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Human Biology 4HB1/01 January 2022

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1. Cardiovascular and circulatory system: heart chamber wall thickness linked to blood pressure, valve function for unidirectional flow, identification of vessels (vena cava, pulmonary vein), blood pathway through heart. 2. Absorption and osmosis: Visking tubing simulates ileum, glucose diffuses due to small size, starch retained due to large molecules, control of contamination via rinsing. 3. Musculoskeletal system: elbow joint structure (tendon, ligament, cartilage), cartilage function in shock absorption and joint smoothness, aging effects (joint pain, restricted movement), tendon role in muscle-to-bone force transfer. 4. Homeostasis and hormones: regulation of blood glucose via insulin and glucagon, glycogen and glucose conversion, ATP generation, negative feedback loop to restore normal glucose levels. 5. Genetics and inheritance: mutation effects on protein structure/function, meiosis and chromosomal aberrations, maternal age impact on mutation risk, genotype analysis indicating female with trisomy (three chromosomes at position 21). 6. Reproductive biology and contraception: vasectomy blocks sperm transport, does not prevent HIV transmission, haploid sperm production site marked, fertilization requires gametes with half chromosome number to maintain diploid state.
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